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Macrinus was the Praetorian prefect during the reign of the murderous Caracalla. Macrinus arranged Caracalla's assassination and he and his son Diadumenian seized power and were accepted by the senate. Macrinus concluded an unfavorable peace with the Persians. This disgrace, magnified by propaganda of Julia Maesa, Caracalla's aunt, inspired the Syrian legions to revolt. In the ensuing conflict Macrinus was defeated. He fled, only to be betrayed and executed.