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Nero became emperor after his stepfather, the emperor Claudius, died (Claudius was probably poisoned by Nero's mother Agrippina II). At first, Nero ruled well, guided by his mentors Seneca and Burrus, but soon his reign degenerated into the debauchery and murder for which he is infamous. He had his mother, Burrus, Britannicus, and numerous senators and members of the nobility murdered or executed. Legend says he kicked Poppaea, his pregnant wife, to death. He was the first emperor to persecute Christians, blaming them for the Great Fire in 64 A.D. Nero committed suicide in 68 A.D. after generals in Africa, Gaul, and Spain all rebelled, and the Praetorian Guard in Rome deserted him.