Pekka's link is a bit
misleading, because the coin and its description are contradictory and do not match the coin presented here
The latter has the legend
AΠAMEΩN THΣ IEΡAΣ KAI AYTONOMOY, so it has been minted after 40/39 BC when Apameia
was granted autonomy by Antony. Before that the legend
has been AΠAMEΩN THΣ IEΡAΣ KAI AΣΥΛOΥ.
To the left of the corn
ears on the reverse
can be seen EOΣ, standing for the minting year 275 in the Seleucid era
, corresponding to 38/37 BC.
Below the corn
ears there are the additional letters AN what probably stands for a magistrate.
An exact reference including year and magistrate is SNG Copenhagen
This and even more information can be found in the thesis of Jack Nurpetlian, "Coinage in late Hellenistic and Roman Syria
: the Orontes
Valley (1st century BC-3rd century AD)", University of Warwick 2013, to be found online here